Yangcheng Evening News reporter Xue Renzheng correspondent Ling Weiming
On April 21st, the team of Zhang Huijie from the Department of Endocrinology and Metabolism of Southern Hospital of Guangdong Southern Medical University published a research paper entitled "Calorie restriction with or without time-restricted eating in weight loss" online in the international authoritative journal New England Journal of Medicine. The results show that after 12 months’ intervention, the average weight of the time-limited dieters decreased by 8.0kg compared with the baseline, which is similar to that of the conventional energy restriction, and the diet also has obvious effects in improving metabolic risk factors such as blood pressure, blood sugar and blood lipid levels.
A 12-month controlled experiment was conducted on 139 people.
In recent ten years, obesity has become a major public health problem that seriously affects the physical and mental health of Chinese people. Studies have shown that obesity is mostly caused by excess energy caused by excessive calorie intake and reduced activity. Time-limited diet is a popular fast food mode, which limits the daily eating time window to 8 to 10 hours, and has attracted much attention because it is simple and effective in reducing weight, improving insulin resistance and metabolic disorder. However, the long-term efficacy of time-limited diet needs further verification, especially the long-term clinical efficacy of time-limited diet in weight loss and metabolic improvement has not been fully evaluated compared with simple energy restriction.
During the 12-month clinical study, the team strictly screened 139 obese adults and randomly divided them into time-limited diet group and conventional energy restriction group.
"Our culture has ‘ Don’t eat after noon ’ Therefore, we chose the time to restrict diet from 8: 00 to 16: 00. " According to Zhang Huijie, only calorie-free drinks are allowed outside the 8-hour limited eating period, while the regular energy restriction group does not limit any eating time. Both groups received the same energy restriction, and the intervention lasted for 12 months. The research team has nutritionists to provide dietary guidance to obese patients throughout the process, including providing recipes and food collocation selection guidance.
During the experiment, the research team conducted face-to-face follow-up for all obese patients once or twice a month, made weight measurement, assessed dietary compliance, and helped solve the difficulties in implementation, and conducted online follow-up by phone or WeChat once or twice a week to complete dietary supervision and guidance, while the time-limited diet group also received the supervision and guidance of time-limited diet. "Our experiment has more samples and longer intervention time than similar research." Zhang Huijie said.
Time-limited diet is similar to limiting energy intake.
It was found that the average energy intake of obese patients was significantly lower than that before intervention under the intervention of time-limited diet and conventional energy restriction, and both dietary patterns were well followed by patients, and the dietary compliance rate of both groups was above 80%.
After 12 months of intervention, the average weight of patients in the time-limited diet group was 8.0kg lower than that in the baseline, and the average weight of patients in the conventional energy restriction group was 6.3kg, which was equally effective in both groups. Compared with before intervention, the waist circumference of obese patients in time-limited diet group decreased by 8.6 cm, and that of patients in conventional energy restriction group decreased by 7.2 cm.
In addition, compared with conventional energy restriction, 8-hour time-limited diet has similar effects in improving metabolic risk factors such as blood pressure, blood sugar and blood lipid levels.
Time-limited diet is safe, effective and easy to operate.
Zhang Huijie introduced that during the 12 months of dietary intervention, there were no serious adverse events in obese patients, only some patients had mild fatigue, dizziness or gastrointestinal discomfort, and they were all improved after adjusting their diet.
Zhang Huijie believes that a time-limited diet such as "no food after noon" can achieve the effect of controlling calorie intake relatively simply. "If the conventional calorie control method is adopted, the calorie intake should be strictly calculated for three meals, which is difficult for ordinary people to operate and adhere to. It will be easier to operate by adopting a time-limited diet and eating one meal less directly. Our research also shows that time-limited diet is a safe, effective and alternative way of weight management. "
Zhang Huijie introduced that the research results made it clear for the first time in the world that the obesity treatment mode of time-limited dieting mainly benefited from energy restriction, which innovated the traditional understanding of dieting mode in the past and provided innovative clinical evidence for the clinical practice of dietary intervention for obese patients.